Smart Neurostimulation
for Brain Recovery & Health
Science & IP
From Vagus Nerve Activation
to Improved Brain Health
Our research demonstrates that auricular vagus nerve stimulation activates brain networks involved in autonomic regulation, neuromodulation and neuroplasticity, supporting its therapeutic potential in neurological and psychiatric conditions.
Mechanism of action
Auricular stimulation
(ABVN)
Nucleus Tractus
Solitarius (NTS)
Neuromodulatory
networks (LC, etc.)
Autonomic modulation
& neuroplasticity
Scientific evidence driving innovation
Anatomical evidence
Auricular vagal targets
Neurophysiological evidence
Responses to auricular stimulation
Clinical evidence
Effects on brain function
Our research provides anatomical, neurophysiological and clinical evidence for the optimal stimulation of auricular vagal targets and their effects on brain function.
Selected XANA publications
Gurtubay I. et al.
2023
Publication details
Immediate effects and duration of a short and single application of transcutaneous auricular vagus nerve stimulation on P300 event-related potential.
Frontiers in Neuroscience, 17.
Gurtubay I.G. et al.
2021
Publication details
Evaluation of different vagus nerve stimulation anatomical targets in the ear by vagus evoked potential responses.
Brain and Behavior, 11(11).
Bermejo P. et al.
2017
Publication details
Innervation of the Human Cavum Conchae and Auditory Canal: Anatomical Basis for Transcutaneous Auricular Nerve Stimulation.
BioMed Research International, 2017.
Intellectual property
Patented miniaturized electronics
Patent portfolio
Títulos, números y enlaces pendientes de incorporar.
Smart Neurostimulation
for Brain Recovery & Health
Get in touch
XANA STIM Sàrl
Switzerland Innovation Park
2822 Courroux, Switzerland
© 2026 XANA STIM. All rights reserved.